The Real Madrid box-to-box man has become an important figure in Joachim Löw’s midfield, and there are concerns that he will not be fit in time to feature at the World Cup.
Khedira has been ruled out for the rest of the domestic club season, with the 26-year-old facing a battle against time to be fit for the competition in Brazil.
With Bastian Schweinsteiger likely to take up one of the central midfield positions in the nation’s 4-2-3-1 formation, who are the contenders to take Khedira’s place if he is unavailable?
The 30-year-old has fitted seamlessly into the Bayern midfield, with his industrious work-rate, poise on the ball and leadership immediately apparent.
With his club partnership with Schweinsteiger and the pair more than likely playing together week-in, week-out in the Bayern midfield once the former comes back from injury, it makes sense. Having the captain and vice-captain in the boiler room could be an inspired move.
One of Khedira’s qualities is his tireless work-rate, but the introduction of the Bayer Leverkusen man could see an even more energetic player take his place.
Bender has been starring at club level, and would be an ideal foil for Schweinsteiger due to his stamina and combativeness, allowing the Bayern man to run the possession game.
A viable option, Bender has very similar attributes to the man that Germany may have to replace.
The Borussia Dortmund midfielder has injury concerns of his own currently, but if he can get back to the form he displayed last term he will certainly be on the plane to Brazil.
Gündoğan’s range of passing is arguably better than Khedira’s, and there was every chance that the Dortmund man would be pushing for inclusion even if Low had all his options available to him.
A supremely able playmaker, Germany would not be weakened if Gündoğan was to replace Khedira.
Lars’ twin brother, the Dortmund man is less experienced at international level, but has been a key part in his club side’s rise to prominence over the last number of seasons.
Sven Bender would be a more defensive choice from Löw, but his presence would tighten things up in the centre of the park and allow the players ahead of him more freedom to concentrate on attacking play.
Worthy of more game time for his country, in a tight match against a competition favourite, the Dortmund man could be a very effective midfield enforcer.
Playing in a similar role in Gelsenkirchen to Khedira in Madrid, Neustädter could well be the workhorse that Germany need to allow others to flourish.
He only has two international caps to his name, but is capable of increasing this considerably if he can continue the clear progression he has made since signing for Schalke last summer.